Figure 6: hOXR1-MSCs treatment alleviated lupus nephritis in B6.Sle1.Sle2.Sle3 mice. (A) BUN (mg/dL). (B) 24 hr proteinuria (mg/24 hr). (C-D) Representative images were PAS stained renal sections from pCDH-MSCs injected, or hOXR1-MSCs injected B6.Sle1.Sle2.Sle3 mice. (C) Exemplified is some of the light microscopic features seen in lupus nephritis with pCDH-MSCs treatment. (D) Please note the improved renal histological changes after treatment with hOXR1-MSCs. No significant tubulointerstitial changes were observed. (E) Renal pathological score in the two groups of mice. (Original magnification 400X, scale bars=50 μm). Each group had 5 mice.