Trial name /Author Year Study design Number of patients Product Route of administration Follow-up duration Outcomes
Total Treated Control
Huang et al.[53] 2007 RCT 150 150 0 BM-MNCs (n=74)
G-CSF-mobilized PB-MNCs
(n=76)
IM 12 weeks ABPI ↑, Skin temperature ↑,
Rest pain scale ↓ in the G-CSF-mobilized PB-MNC treated group.
No significant difference in TcPO2 ,
pain-free walking distance,
Ulcer healing and amputation rate.
Table 3: Clinical trials of autologous BM-MNCs versus G-CSF-mobilized PB-MNCs for CLI.