Variables Total Contact Lenses Amniotic membrane p* m (IQR) m (IQR) m (IQR) Pain 9.5 (7.5–10) 9.5 (7 -10) 9.5 (8–10) 0.75 (visual analogue scale) Corneal neovascularization 0 (0–2) 0.5 (0 -2) 0 (0–2) 0.97 (by quadrants) Bullae 0 (0–2) 0.5 (0 -2) 0 (0–2) 0.48 (by quadrants) Visual sharpness 0.0052 (0.0052–0.014) 0.0052 (0.0052–0.014) 0.0096 (0.0033–0.014) 0.84 (Snellen)

Table 2: Distribution of study variables in each group before inclusion of each patient in the clinical trial. P values correspond to the statistical comparison of each variable between the control and the AM group. m: Median; IQR: Interquartile Range.