Totipotent stem cells; zygote + 2 to 4 cell embryo |
These cells are capable of giving rise to the entire organism (both embryonic and non-embryonic tissues) |
Multipotent stem cells; adult stem cells |
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Pluripotent stem cells; embryonic stem cells and embryonic germ cells |
These cells can give rise to derivatives of all 3 germ layers [embroynic tissue only and not extraembryonic tissues]
Embryonic stem cells (ESCs) have the potential to form any cell type in the body.
Pluripotent stem cells (PSCs) can be divided into 2 types
[a] Embryonic stem cells (ESCS): derived from the inner cell mass of the mammalian blastocyte.
[b] Induced pluripotent stem cells (iPSCs): somatic cells reprogrammed to a pluripotent state by exogenous expression of transcription factors responsible for conferring pluripotency on ESCs. |