1.Disease modeling
2. Regenerative medicine: tissue engineering and organ repair
3. Drug screening for toxicity, drug development and drug discovery
4. Genetic therapy; treatment of intractable and genetic disorders:
** Sickle cell anemia ** Cystic fibrosis
** β- Thalassemia ** Lysch - Nyhan syndrome
** Hemophilia ** Hurler syndrome
** Fanconi anemia ** Pompe disease
** Dyskeratosiscongenita ** Wilson disease
** Schwachman-Bodian-Diamond syndrome ** Down's syndrome
** Primary myelofibrosis ** Huntington's disease
** Polycythemia rubravera ** Parkinson's disease
** Epidemolysisbulosae ** Alzheimer's disease
** Retinitis pigmentosa ** Schizophrenia
** Spinal muscular atrophy ** Ducchene muscular dystropy
  ** Amyotrophic lateral sclerosis
5. Cell-based therapies.
6. Synthesis of blood components: the following blood components haveĀ  been generated from embryonic and iPSCs:
[a] Red blood cells [definitive and primitive erythroid cells]; can be used in severe anemia or blood loss.
[b] Megakaryocytes and platelets; transfusion in critical thrombocytopenia
[c] Dendritic cells: antigen-specific vaccines for cancer or human immunodeficiency virus (HIV)
[d] Natural killer cells: natural or antibody-assisted anticancer cytotoxicity
[e] T- lymphocytes: antigen-specific anti-cancer or anti- HIV adoptive cell transfer.
[f] B- lymphocytes
[g] Neutrophils
[h] Monocytes and macrophages
Table 6: Clinical applications of iPSCs.