Advantages |
Disadvantages |
Avoidance of using human embryos |
Use of integrative DNA methodology |
Capacity to induce stem cell like phenotype |
Genomic instability and aberrations |
New promises to cellular therapy |
Increased risk of cancer development due to the use of oncogenes for the induction of iPSCs phenotype. |
Possibility of studying several diseases including cancer |
Immunogenicity of iPSCs and rejection potential. |