Advantages Disadvantages
Avoidance of using human embryos Use of integrative DNA methodology
Capacity to induce stem cell like phenotype Genomic instability and aberrations
New promises to cellular therapy Increased risk of cancer development due to the use of oncogenes for the induction of iPSCs phenotype.
Possibility of studying several diseases including cancer Immunogenicity of iPSCs and rejection potential.
Table 7: Advantages and disadvantages related to the utilization of iPSCs.