Figure 2: Histopathological examination of microglia infiltration in RR-EAE rats.A) Representative sections were obtained from lumbar spinal cords of untreated CTRL rats, EAE rats, and EAE rats treated with MSCs injected after 7 (T7) or 14 days after the immunization (T14). Sections were immunostained with anti- ED1, a marker of active microglia, and hematoxilin. Scale Bar 50 μm. Arrow indicated the microglial infiltration. B) The sections were then analyzed to quantify the inflammatory infiltrate ImageJ software. These measures were expressed as mean ± SD. *P< 0.05, EAE+MSC T14 vs. EAE.