Figure 6: Cell relative survival rates of different culture models (2D, 3D, 3D coculture) after medicated by middle concentration AP (400 µg/L), 5-FU (50 µg/ml) and matrine (0.15 mg/ml) for 4 days. Significant differences were found among the 2D, 3D, 3D coculture groups containing pure hepatocytes or ADSC/ hepatocyte mixtures (P<0.05).