Figure 7: Cell relative survival rates of 3D model after medicated by AP, 5-FU and matrine with three different concentrations: high concentration (H) AP 4 mg/ml, 5-FU 500 µg/ml, matrine 1.5 mg/ml, middle concentration (M) AP 400 µg/L, 5-FU 50 µg/ml, matrine 0.15 mg/ml, and low concentration (L) AP 40 µg/L, 5-FU 5 µg/ml, matrine 15 µg/ml. Significant differences were found among the three different AP concentrations (P<0.05).