FFA (%) Men (n =122) Women (n = 119)   Model 1 Model 2 Model 1 Model 2   r p β p r p β p Total SFA -0.717** <0.001 -0.581** <0.001 -0.489** <0.001 -0.284** 0.009 C14:0 -0.240 0.117 -0.101 0.453 -0.003 0.979 0.130 0.184 C16:0 -0.646** <0.001 -0.450** <0.001 -0.350** 0.006 -0.215* 0.037 C18:0 -0.393** 0.008 -0.358* 0.005 -0.376** 0.003 -0.127 0.232 Total MUFA 0.292 0.054 0.021 0.883 0.132 0.309 0.131 0.171 C16:1 -0.180 0.242 -0.089 0.451 -0.164 0.206 -0.116 0.223 C18:1 0.394** 0.008 0.144 0.310 0.089 0.494 0.133 0.170 Total PUFA 0.464** 0.002 0.378* 0.001 0.336** 0.008 0.211* 0.035 Total n-3 0.202 0.188 0.081 0.520 0.584** <0.001 0.392** <0.001 C18:3  0.326* 0.031 0.192 0.139 0.165 0.205 0.170 0.078 C20:5 0.045 0.773 0.121 0.370 0.066 0.612 0.042* 0.737 C22:5 0.311* 0.040 0.099 0.438 0.410** 0.001 0.237* 0.018 C22:6 0.110 0.477 0.033 0.795 0.562** <0.001 0.341** <0.001 Total n-6 0.425* 0.004 0.374** 0.001 0.217 0.093 0.142 0.158 C18:2 0.178 0.249 0.225 0.055 0.260* 0.043 0.148 0.154 γ-C-18:3 0.507** <0.001 0.422** 0.002 0.286* 0.025 0.163 0.093 C20:3 -0.005 0.974 -0.029 0.813 -0.104 0.426 -0. 026 0.802 C20:4 0.383* 0.010 0.397** 0.001 0.003 0.980 0.071 0.461 D9D-16(16:1n-7/16:0) 0.181 0.240 0.279 0.061 0.050 0.699 0.026 0.793 D9D-18(18:1n-9/18:0) 0.484** 0.001 0.373** 0.006 0.275* 0.032 0.012 0.907 D6D(18:3n-6/18:2 n-6) 0.407 0.006 0.191 0.168 0.367** 0.004 0.216* 0.034 D5D(20:4n-6/20:3 n-6) 0.006 0.968 0.046 0.728 0.047 0.719 0.049 0.630

Table 4: FFAs compositions and desaturase activities correlated with the serum DHEA-S levels by Spearman. correlation analysis and Multiple linear regression analysis (* p < 0.05; ** p < 0.01; Model 1: Spearman correlation coefficient. Model 2: Regression coefficient adjusted for age, BMI, TG, TC 2h-PG and fasting insulin).