Mayo index 0 1 2 3 Stool frequency Normal 1-2/day > normal 3-4/day > normal 5/day > normal Rectal bleeding None Obvious Streaks Mostly blood Mucosa Normal Mild friability Moderate friability Spontaneous bleeding Global assessment Normal Mild Moderate Severe

Table 1b: Patients with a Mayo score of6 or more have moderately to severely active disease and may be uncontrolled.