Figure 6: a) new bone was observed surrounding some particles (NB). Bone formation was observed at both margins of the defect, and this was more evident at one of the margins. Acid fuchsin and toluidine blue 2X,Scale bar=1mm; b) previous image at higher magnification. New bone (NB) surrounded the biomaterial particles (ß-TCP). New bone extended also in central part of the bone defect. Fibrous tissue and biomaterial with a mild multinucleated cells reaction (arrows). Acid fuchsin and toluidine blue 100X.