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Figure 2: Study protocol and administration of spermine-treated hADMPCs. (A) From day 5 before cell transplantation to the end of the experiment, the animal received CyA for immunosuppression. At day 0, the animals with chronic severe MI were applied for the experiment. (B) At day 0, pigs with experimentally-induced chronic myocardial infarction were transplanted with spermine-treated hADMPCs via the left anterior descending coronary artery (LAD #6). |