Figure 3: Effects of transplantation of spermine-treated hADMPCs on cardiac function. (A) RAO view of left ventriculography (LVG) performed at day 0 (top 2 panels) and 12 weeks after transplantation (bottom 2 panels) in a representative animal. (B) Cardiac function was assessed by echocardiography before and every 4 weeks after transplantation. The left ventricular ejection fraction (EF) and ΔEF improved in the transplantation group, but not in the control group. The most effective dose was 3x105 cells/kg body weight.