The apoptosis in H-GMSCs at 0, 50, 100, 200, 500 and 1000 nM TSA or LBH589. The apoptosis rates in H-GMSCs were treated by different concentration of TSA or LBH589. The dose of 1000 nM most effectively induced propidium iodide-positive, annexin-positive apoptosis (n=5, P<0.05, one-way analysis of variance).

Figure 5: Exposure to TSA or LBH589 induces H-GMSCs apoptosis in a dose-dependent manner.