Exposure to TSA or LBH589 arrested cell-cycle progression at G1/S, as revealed by flow cytometry. Propidium iodide staining and flow cytometry confirmed that the percentage of H-GMSCs in G1 increased after adding TSA. H-GMSCs in G1 increased after addingLBH589. Propidium iodide-stained cells=S cells+G2 cells/G1 cells+S cells+G2 cells; n=5, P<0.01; one-way analysis of variance).

Figure 6: TSA and LBH589 influence cell-cycle progression in H-GMSCs.