markers
Statistically significant differences in overall mean mutation frequencies were observed between EBs from H1 and H7 ES cell lines. (A) Overall mean values for mutation frequencies of unstable markers observed in EBs from the H1 ES cell line. (B) Overall mean values for mutation frequencies of unstable markers observed in EBs from the H7 ES cell line. Values represent the overall mean mutation frequency of EB sample replicates (n=144) per marker that was calculated with SP-PCR software (MD Anderson Cancer Houston, TX). Markers show statistically significant differences p ≤ 0.05 except for D6S2252 and D4S2623 that show marginally significant differences *p ≤ 0.10.
Figure 6: Unstable markers of embryoid bodies differentiated from H1 and H7 ES cell lines.