| The stem cell marker Nestin was observed in pericytes (PCs) near Cluster of differentiation (CD) 31+ endothelial cells during early development (Embryonic Day 17
[E17], Postnatal Day 1 [P1], and P8), but was rare during adulthood (8 and 24 weeks). Nestin (A: green); CD31 (A: red); 4’,6-diamidino-2-phenylindole (DAPI; A: blue;
arrows). Some Nestin+ cells in brains at E17 co-expressed neuron-glial antigen 2 (NG2). Nestin (B: green); NG2 (B: red); DAPI (B: blue; arrows). The number of Nestin+
PCs at each developmental stage is shown (C). Scale bars = 50 μm (A, B). |
