Symbol |
Description |
ALDHbr |
ALDHdim |
ALDHbr vs. ALDHdim |
mean ΔCt |
SD |
mean ΔCt |
SD |
Fold change |
p value |
Most highly expressed genes in ALDHbr cells |
ENG |
CD105 [endoglin] |
4.31 |
0.95 |
10.38 |
1.44 |
66.93 |
0.04 |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
4.78 |
0.23 |
5.26 |
0.11 |
1.39 |
0.03 |
IL8 |
Interleukin 8 |
4.79 |
1.59 |
2.11 |
0.20 |
-6.38 |
<0.001 |
TGFB1 |
Transforming growth factor, beta 1 |
5.39 |
0.52 |
4.05 |
0.59 |
-2.54 |
0.03 |
EREG |
Epiregulin |
5.41 |
0.90 |
6.11 |
0.27 |
1.63 |
0.20 |
EPHB4 |
EPH receptor B4 |
5.94 |
0.59 |
11.96 |
0.23 |
64.60 |
0.01 |
AKT1 |
V-akt murine thymoma viral oncogene homolog 1 |
6.02 |
0.76 |
7.10 |
0.13 |
2.11 |
0.10 |
HIF1A |
Hypoxia inducible factor 1, alpha subunit |
6.60 |
0.51 |
5.44 |
0.23 |
-2.24 |
0.01 |
SPHK1 |
Sphingosine kinase 1 |
7.06 |
0.78 |
10.28 |
0.22 |
9.30 |
0.01 |
COL18A1 |
Collagen, type XVIII, alpha 1 |
7.30 |
0.91 |
10.76 |
0.73 |
10.97 |
0.03 |
VEGFA |
Vascular endothelial growth factor A |
7.39 |
0.84 |
7.91 |
0.03 |
1.43 |
0.24 |
TIMP2 |
TIMP metallopeptidase inhibitor 2 |
8.00 |
1.26 |
6.02 |
0.82 |
-3.95 |
0.08 |
ANPEP |
Alanyl (membrane) aminopeptidase |
8.36 |
1.85 |
7.21 |
1.00 |
-2.23 |
0.28 |
S1PR1 |
Sphingosine-1-phosphate receptor 1 |
8.53 |
0.39 |
4.81 |
0.70 |
-13.15 |
0.01 |
FGFR3 |
Fibroblast growth factor receptor 3 |
8.80 |
0.62 |
12.25 |
0.43 |
10.87 |
0.01 |
MMP2 |
Matrix metallopeptidase 2 (Collagenase) |
8.83 |
1.43 |
13.31 |
0.27 |
22.44 |
0.07 |
MDK |
Midkine (neurite growth-promoting factor 2) |
9.03 |
1.21 |
11.13 |
0.64 |
4.28 |
0.11 |
MMP9 |
Matrix metallopeptidase 9 (Collagenase) |
9.18 |
0.92 |
2.44 |
0.94 |
-106.64 |
0.02 |
ID1 |
Inhibitor of DNA binding 1 |
9.33 |
0.39 |
8.49 |
0.33 |
-1.79 |
0.02 |
PTGS1 |
Prostaglandin-endoperoxide synthase 1 |
9.40 |
0.54 |
12.21 |
0.74 |
7.01 |
0.02 |
PROK2 |
Prokineticin 2 |
9.45 |
2.37 |
7.44 |
1.44 |
-4.02 |
0.33 |
TYMP |
Thymidine phosphorylase |
9.50 |
0.38 |
6.62 |
0.67 |
-7.34 |
0.01 |
SERPINF1 |
EDG1 |
9.61 |
0.77 |
9.86 |
0.56 |
1.19 |
0.55 |
IL1B |
Interleukin 1, beta |
9.63 |
1.44 |
6.83 |
0.46 |
-6.97 |
<0.001 |
PECAM1 |
CD31 |
9.69 |
2.57 |
7.90 |
6.91 |
-3.45 |
0.29 |
Other genes differentially expressed in ALDbr vs. ALDHdim cells |
TEK |
TEK tyrosine kinase, endothelial |
10.57 |
1.12 |
13.32 |
0.52 |
6.75 |
0.14 |
TNFAIP2 |
Tumor necrosis factor, alpha-induced protein 2 |
10.78 |
0.62 |
8.53 |
0.19 |
-4.77 |
<0.001 |
CXCL1 |
Chemokine (C-X-C motif) ligand 1 |
10.82 |
1.77 |
7.64 |
1.42 |
-9.10 |
0.11 |
THBS1 |
Thrombospondin 1 |
10.97 |
1.69 |
8.24 |
1.18 |
-6.64 |
0.05 |
ID3 |
Inhibitor of DNA binding 3 |
10.99 |
0.49 |
7.51 |
0.16 |
-11.14 |
<0.001 |
ANGPT1 |
Angiopoietin 1 |
11.15 |
0.81 |
13.94 |
0.90 |
6.96 |
0.03 |
TNF |
Tumor necrosis factor |
11.76 |
1.22 |
6.17 |
0.74 |
-48.27 |
0.01 |
EFNB2 |
Ephrin-B2 |
12.66 |
0.95 |
11.10 |
0.41 |
-2.94 |
0.03 |
VEGFC |
Vascular endothelial growth factor C |
12.99 |
1.96 |
10.19 |
5.73 |
-6.96 |
0.29 |
IL6 |
Interleukin 6 (interferon, beta 2) |
13.96 |
0.45 |
9.22 |
0.96 |
-26.86 |
0.04 |
IFNG |
Interferon, gamma |
13.99 |
0.92 |
7.66 |
0.89 |
-80.49 |
0.01 |
PLXDC1 |
Plexin domain containing 1 |
14.00 |
1.12 |
11.23 |
1.77 |
-6.83 |
0.13 |
CXCL6 |
Chemokine (C-X-C motif) ligand 6 |
14.69 |
0.70 |
10.38 |
1.08 |
-19.87 |
0.05 |
KDR |
Kinase insert domain receptor/VEGF receptor |
15.08 |
1.22 |
13.24 |
0.61 |
-3.60 |
0.03 |
COL4A3 |
Collagen, type IV, alpha 3 |
15.19 |
1.22 |
13.55 |
0.44 |
-3.10 |
0.04 |
HAND2 |
Heart and neural crest derivatives expressed 2 |
15.19 |
1.22 |
13.30 |
0.54 |
-3.70 |
0.02 |