| Histological parameters |
| Group |
Infarct size (percent) |
Scar thickness (mm) |
Expansion index* |
Akinesis & dyskinesis (%) |
| hESC-CM |
28.7 ± 5.5 |
1.3 ± 0.21 |
0.27 ± 0.11 |
8.96 ± 1.9 |
| MSC+CM |
35.7 ± 4.1 |
1.52 ± 0.28 |
0.31 ± 0.08 |
8.37 ± 1.67 |
| HO-1 MSC+CM |
30.8 ± 4.2 |
1.25 ± 0.14 |
0.36 ± 0.07 |
4.57 ± 1.00 |
| saline |
42.5 ± 2.8 |
0.71 ± 0.04 |
0.71 ± 0.05 |
10.73 ± 1.76 |
| p value |
0.166 |
0.091 |
0.0039 |
0.056 |
*For expansion index, there was a significant group effect by ANOVA (p=0.0039).
Tukey's test showed that the expansion index was significantly higher in the
control group versus each of the 3 cell-treated groups (p < 0.05). |
