| Year |
Authors |
Animal Model |
Disease |
Inflammatory Findings |
| 2003 |
Nakae, et al. |
Mouse |
Arthritis |
IL-17 deficient mice did not develop arthritis |
| 2007 |
Maccoux, et al. |
Dog |
Osteoarthritis |
Increased IL-1β, IL-6, IL-10 in synovial fluid |
| 2007 |
Ley, et al. |
Horse |
Osteoarthritis |
Increased IL-6 in synovial fluid |
| 2007 |
Huebner, et al. |
Guinea Pig |
Osteoarthritis |
Increased IL-6 in serum |
| 2009 |
Kato, et al. |
Rat |
Neuropathic Pain |
Decreased TNF-α expression correlated with less pain |
| 2009 |
Sekiguchi, et al. |
Rat |
Neuropathic Pain |
Increased TNF-α in L5 nerve root injury |
| 2011 |
Liao, et al. |
Mouse |
Neuropathic Pain |
Increased IL-1β expression in spinal cord |
| 2011 |
Kim, et al. |
Mouse |
Neuropathic Pain |
Lack of IL-17 resulted in decreased pain |
| 2011 |
Yuan, et al. |
Mouse |
Arthritis |
IL-21 deficient mice did not develop arthritis |
IL=interleukin, TNF=tumor necrosis factor |
