| Year |
Authors |
Disease |
Sample |
Inflammatory Findings |
| 2005 |
Alexander et al. |
Complex Regional Pain Syndromes |
Cerebral Spinal Fluid |
Increased IL-6 and IL-1β |
| 2007 |
Uceyler, et al. |
Complex Regional Pain Syndromes |
Serum |
Increased IL-2 and TNF-α. Decreased anti-inflammatory IL-4 and IL-10 |
| 2009 |
Doupis, et al. |
Painful Diabetic Peripheral Neuropathy |
Serum |
Higher levels of TNF-α in painful versus painless diabetic peripheral neuropathy |
| 2009 |
Lee, et al. |
Degenerative Disc Disease |
Intervertebral Disc |
Higher levels of TNF-α and IL-8 |
| 2010 |
Kraychete, et al. |
Herniated Disc |
Serum |
Greater levels of IL-6 and TNF-α |
| 2010 |
Cuellar, et al. |
Degenerative Disc Disease |
Disc Fluid |
Increased IFN-gamma |
| 2010 |
Kim, et al. |
Osteoarthritis |
Cartilage |
TNF-α and IL-1β caused more damage to mitochondria of OA tissue than normal tissue |
| 2011 |
Levinger, et al. |
Osteoarthritis |
Muscle |
Higher levels of IL-6, IL-1β, and TNF-α |
| 2011 |
Purwata, et al. |
Painful Diabetic Peripheral Neuropathy |
Serum |
Higher levels of TNF-α |
| 2011 |
Orita, et al. |
Osteoarthritis |
Synovial Fluid |
Higher levels of IL-6 and TNF-α |
IL=interleukin, TNF=tumor necrosis factor |
