| Year |
Authors |
Disease |
Model |
Therapy |
Findings |
| 2008 |
Alfaqeh, et al. |
Osteoarthritis |
Sheep |
Autologous MSC injection |
Articular cartilage regeneration |
| 2008 |
Shibata, et al. |
Diabetic Polyneuropathy |
Rat |
Autologous MSC injection |
Improved hypoalgesia, sural nerve blood flow, and nerve conduction velocity |
| 2008 |
Centeno, et al. |
Osteoarthritis |
Human |
Autologous MSC injection |
Regeneration of meniscus cartilage |
| 2010 |
Yoshikawa, et al. |
Degenerative Disc Disease |
Human |
Autologous MSC injection |
Disc regeneration and decrease in back and leg pain |
| 2011 |
Orozco, et al. |
Degenerative Disc Disease |
Human |
Autologous MSC injection |
Decrease in pain and disability |
| 2011 |
Guo, et al. |
Chronic Pain |
Rat |
Autologous MSC injection |
Reversed mechanical hypersensitivity |
| 2011 |
Waterman and Betancourt |
Painful Diabetic Peripheral Neuropathy |
Mouse |
Human MSC2 injection |
Decreased serum inflammatory cytokines, improved heat hyperalgesia and mechanical allodynia |
MSC=multipotent mesenchymal stromal cells frequently referred to as mesenchymal stem cells, MSC2=anti-inflammatory mesenchymal stem cells |
