Variable Patient No. Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Case 7 Case 8 Sex F F F F F M F M Age at onset, y 52 52 26 25 22 14 49 36 Age at study enrollment, y 59 57 41 30 26 18 54 40 Relapses since disease onset, no. 21 3 5 12 3 3 3 2 Visual evoked potential Abnormal Abnormal Abnormal Abnormal Abnormal Abnormal Abnormal Abnormal Previous therapy CS, IVIG CS, IVIG CS, IFN, OA CS, IFN CS CS, IFN CS, IVIG CS, IVIG Abbreviations: CS: corticosteroids; IVIG: Intravenous Immunoglobulin; IFN: Interferon; ON: Optic Neuritis; TM: Transverse Myelitis; OA: Oral Azathioprine.

Table 2: Characteristics of MS patients.