Figure 2: Panel A. Differentiating agent which acts on progenitors cells results in an increase in the overall number of cells and establishment of new equilibrium at a higher level. Panel B. Differentiating agent which acts on transit amplifying cells decreases the overall cell number but establishes am equilibrium at a level which is similar to that of stem cell antagonists. Panel C. Differentiating agent which acts on differentiated cells produces the most pronounced suppression on tumor cell population but nevertheless contributes to the formation a new but lower equilibrium.