Figure 2: Schematic representation of the relevant mechanisms underlying the functional benefits of MSC- and CSC- and growth factor/cardiotropic hormonebased therapy. Abbreviations: CSCs: Cardiac Stem/Progenitor Cells; ECM: Extracellular Matrix; FGF: Fibroblast Growth Factor; HGF: Hepatocyte Growth Factor; IGF-1: Insulin Growth Factor-1; IL-1: Interleukin 1; IL 6: Interleukin-6; IL-10: Interleukin-10; IL-1RA: Interleukin 1 Receptor Antagonist; LIF: Leukemia Inhibitory Factor; MMPs: Matrix Metalloproteinases; MSCs: Mesenchymal Stromal Cells; NO: Nitric Oxide; PDGF: Platelet Derived Growth Factor; PGE2: Prostaglandin E2; SDF-1: Stromal Derived Factor-1; TGF-β: Transforming Growth Factor-β; VEGF: Vascular Endothelial Growth Factor.