Physical Matrix Fluid condition Dehydrated condition
Type II Collagen Fibril D-spacing 67.9 ± 1.2 nm 65.8 ± 0.8 nm
Type II Collagen Fibril Diameter 180 ± 30 nm, 20 ±10 nm 180 ± 50 nm
Average Roughness 9.93 ± 1.10 nm 41.0 ± 11.8 nm
Surface Area 12.1 um2 20.2 um2
Table 1: Morphological parameters measured from AFM images. All measurements were performed on 3.5 mm size AFM images.