Figure 4: Optimized transition state geometry for the guanine attack on A) monoaquated cisplatin from gas-phase: Pt(NH3)2Cl(OH2)(guanine) (1b); B) monoaquated cisplatin from gas-phase: Pt(NH3)2Cl(OH2)(guanine) (1b); C) monoaquated BNP3029 from gas-phase: Pt[N≡C(CH2)3(C6H5)]2Cl(OH2) (guanine) (3b). All distances are in Angstroms (Å) and angles are in degrees.