Entry |
Substrate |
Reagent |
Product |
Time (min) |
Yieldb (%) |
1 |
 |
(CH3CO)2O |
 |
70 |
90 |
2 |
 |
(CH3CO)2O |
 |
85 |
84 |
3 |
 |
(CH3CO)2O |
 |
80 |
86 |
4 |
 |
4-OMePhCOCl |
 |
95 |
87 |
5 |
 |
PhCOCl |
 |
80 |
89 |
6 |
 |
(CH3CO)2O |
 |
95 |
85 |
7 |
 |
PhCOCl |
 |
90 |
83 |
8 |
 |
PhCOCl |
 |
95 |
83 |
9 |
 |
(CH3CO)2O |
 |
90 |
88 |
10 |
 |
(CH3CO)2O |
 |
100 |
86 |
11 |
 |
(CH3CO)2O |
 |
110 |
84 |
12 |
(CH3)3CH2SH |
PhCOCl |
 |
105 |
88 |
aAll the products are known compounds and were characterized by comparison of their NMR spectral data and physical properties with those reported in the literature
[11,27,30]. bIsolated yield |