Shiff base Bacteria Gram negative Gram positive B. subtilis S. aureus E.coli S. typhi VI 17mm 18mm 15mm 18mm VII 18mm 16mm 16mm 19mm VIII 18mm 15mm 12mm 17mm Control 00mm 00mm 00mm 00mm Ciprofloxacin 20mm 20mm 20mm 20mm

Table 4: Effect of new macrocyclichydrazone (VI, VII,VIII) on the growth of tested bacteria (conc.200 μg/ml).