Type Endpoint Definition
Human health effects    
Acute Rodent oral LD50 The mass of the substance administered per unit mass of the test subject that will kill half of the test subjects within 14 days when orally administered as a single dose.
Chronic Carcinogenicity Based on supporting evidence.
Chronic Reproductive and Developmental Toxicity
Chronic Endocrine Toxicity
Environmental effects    
Aquatic, acute Fish LC50 The concentration of a substance in water that will cause 50% of fish deaths in the 96 h test.
Terrestrial, acute Bird LD50 The mass of the substance administered per unit mass of the test subject that will kill half of the test subjects within 14 days when orally administered as a single dose.
Exposure potential    
Partition Octanol–water Partition (Kow) The ratio of the distribution of a substance between octanol and water.
Bioaccumulation Bioconcentration factor (BCF) The ratio of the concentration of a chemical in a biological tissue to that in the water surrounding that tissue.
  Human exposure concentration The concentration of a chemical in human adipose tissues.
  Frequency of detection Frequency of detection in human adipose tissue samples.
Table 1: Toxicological and exposure endpoints.