Compound
GI
50
(μM)
a
MCF-7
HCT-15
1a
4.23 ± 0.50
ND
2c
> 5
> 5
6f
2.44 ± 0.25
ND
9d
> 5
3.60± 0.06
Doxorubicin
0.024 ± 0.007
1.07 ± 0.18
Table 2:
Determination of the GI
50
concentration of the most active naphthalimide compounds on different human tumor cell lines.
