Bile acid 1st additiona h 2ndadditionb h 3rd additionc h HADD (Yield %) HADD (Overall yield %)f
1a 24 24 32 2a (95)d 2a (73)
1b 24 48 72-96 2b (23)d 2b(18)
1c 24 24-32 72 2c (52)d 2c (40)
1d 8-9 day -- -- 2d (83)e  
aTime of biotransformation with 1 g/L of bile acids (1a-d) as sodium salt; bTime of biotransformation with 2 g/L of bile acids (1a-c) as sodium salt; cTime of biotransformation with 10 g/L of bile acids (1a-c) as sodium salt; dCalculated on 10 g/L addition; eCalculated on 1 g/L addition; fCalculated on 13 g/L addition.
Table 1: Biotransformation of bile acids 1a-d with Pseudomonas alcaliphila.