S No Starting material Product Reaction time Yield
1 image image 12 h 28 %
2 image image 30 min 75 %
3 image image 15 min 95 %
4 image image 5 h 51 %
5 image image 3 h 80 %
6 NH3 image 10 h 98 %
Reaction condition: 1:1:0.1 Molar ratios of amine: Di-tert-butyl dicarbonate: Molecular sieves respectively at 20-25°C.
Table 1: Synthesized N-BOC protected amines.