S No
Starting material
Product
Reaction time
Yield
1
12 h
28 %
2
30 min
75 %
3
15 min
95 %
4
5 h
51 %
5
3 h
80 %
6
NH
3
10 h
98 %
Reaction condition: 1:1:0.1 Molar ratios of amine: Di-tert-butyl dicarbonate: Molecular sieves respectively at 20-25°C.
Table 1:
Synthesized N-BOC protected amines.