Figure 2: Fetus anomalies. (a) dysmorphic face with single eye and two globes fused medially (synophtalmia), no nose and philtrum, hypotelorism and icrognathia. (b) Profil facies: flat facies, defective relief nasal, dysmorphic large ear with abnormal presence of nodule closed in the trangus on right. Short and broad neck with excess skin. (c) Entire fetus showing extremities anomalies: closed hands and equine feet with prominent heels. (d) Radiographic imaging of cranium presenting severe facial bones anomalies associated with two partial cup orbits, absence of nasal bones and premaxillary agenesis. (e) Cardiac defect: truncus arteriosus communis with hypertrophy of right cavities (auricle and ventricle), left heart hypoplasia with castellated appearance of the auricle. (f) Encephalic anomalies: small brain (dorsal face) represented by a single cerebral mass with partial dorsal of interhemispheric sulcus, signing a semi-lobar holoprosencephaly.