14 days

28 days

42 days

control

184.22±11.29

185.50±12.24

187.52±11.29

5 mg/kg group

180.52±11.25

179.94±12.03

180.58±12.48

15 mg/kg group

177.06±10.91

166.59±11.49**

167.36±10.90**

30 mg/kg group

166.36±10.69**

166.27±10.07**

166.26±10.65**

45 mg/kg group

164.59±10.32**

157.86±10.12**

157.99±10.78**

60 mg/kg group

153.94±9.39**

154.89±10.61**

144.59±10.87**