compound Molecular formula Molecular weight Melting range
°C
Yield (%)
8a C23H28FN5O3S 473.56 79-81 56
8b C24H31N5O3S 469.60 98-101 58
8c C24H28F3N5O3S 523.57 52-54 54
8d C24H31N5O4S 485.60 84-86 62
8e C24H31N5O4S 485.60 78-80 64
8f C23H28ClN5O3S 490.02 100-102 53
8g C27H31N5O3S 505.63 115-118 61
8h C19H29N5O3S 407.53 97-99 51
8i C21H33N5O3S 435.58 92-94 62
Table 1: Physical data of the newly synthesized 9-substituted derivatives of tert-butyl 6-(9H-purin-6-ylthio) hexylcarbamate (8a-8i).