Drugs Regression equation R2 LLOD ng mL-1 LLOQ ng mL-1
Phase-1
Lef y=11428x + 1345.6 0.9998 13 39
Flur y=13149x + 118.64 0.9998 6.9 21
Ibu y=204.9x – 970.43 0.9985 296 897
Phase-2
Lef y=16783x + 7014.6 0.998 13 39
Diclo y=4488.5x – 369.24 0.9992 71 214.3
Mef y=2766.6x + 11798 0.9985 1.2 3.676
Lef=leflunomide, Flur=flurbiprofen, Ibu=ibuprofen, Mef=mefanamic acid,Diclo=diclofenac sodium (n=6)
Table 3: Sensitivity of the proposed methods.