Groups
Treatment/Dose (mg/mL) |
Liver |
Kidney |
Heart |
GSH
mg/100g. tissue |
GPx
U/mg. protein |
SOD
U/mg. protein |
CAT
U/mg. protein |
GSH
mg/100g. tissue |
Gpx
U/mg. protein |
SOD
U/mg. protein |
CAT
U/mg. protein |
GSH
mg/100g. tissue |
GPx
U/mg. protein |
SOD
mg/100g. tissue |
CAT
mg/100g. tissue |
| Normal Control |
142.34
± 5.261 |
17.14
± 2.05 |
13.89
± 3.71 |
65.19
± 4.71 |
101.00
± 8.38 |
8.06
± 1.43 |
10.44
± 2.71 |
43.28
± 3.48 |
115.48
± 9.04 |
13.59
± 2.50 |
9.08
± 1.91 |
27.46
± 2.83 |
| Control + CAMBA (25mg/kg) |
139.68
± 7.90 |
16.05
± 3.22 |
12.44
± 1.75 |
60.34
± 5.38 |
98.07
± 5.40 |
8.11
± 2.07 |
10.25
± 3.13 |
46.08
± 5.23 |
114.50
± 6.37 |
13.33
± 2.01 |
10.26
± 1.79 |
29.04
± 5.26 |
| Control + CAMBA (50mg/kg) |
140.57
± 8.11 |
18.10
± 4.06 |
13.06
± 2.30 |
64.35
± 7.11 |
104.71
± 10.59 |
8.98
± 1.90 |
11.17
± 2.39 |
46.69
± 7.08 |
117.92
± 10.25 |
14.05
± 2.67 |
12.74
± 3.08 |
28.11
± 3.29 |
| Diabetic Control |
87.45
± 5.08** |
7.44
±1.15** |
4.19
±1.33** |
37.94
±4.38** |
55.06
±4.38 |
4.56
±0.58** |
5.94
±1.47** |
27.93
±4.66** |
76.82
±6.08** |
5.99
±1.85** |
6.55
± 1.13** |
15.95
± 2.18** |
| Diabetic + CAMBA (25mg/kg) |
122.73
± 8.46** |
11.82
±2.00** |
7.86
±2.35** |
50.08
±6.26 |
75.97
±6.84 |
6.27
±1.08** |
7.16
±0.57** |
35.00
±4.86** |
84.26
±4.75** |
8.22
±2.04** |
7.72
± 1.94** |
22.49
± 3.30** |
| Diabetic +CAMBA (50mg/kg) |
138.83
± 7.93** |
15.77
±2.57** |
11.46
±3.24** |
59.63
±4.81 |
89.44
±7.65 |
9.63
±2.48** |
10.39
±2.71** |
41.60
±4.22** |
104.13
±7.38** |
11.29
±2.41** |
10.55
± 2.03** |
25.37
± 4.02** |
| Diabetic +Glibenclamide(5mg/kg) |
128.44
± 6.50** |
12.85
±1.48** |
9.59
±2.18** |
54.16
±3.99 |
80.39
±5.07 |
8.15
±1.83** |
9.80
±2.11** |
30.85
±2.79** |
90.44
±8.06** |
9.08
±2.11** |
9.12
± 1.60** |
19.70
± 3.46** |
Values represent the mean ± SE (n=8). Diabetic control rats were compared with normal control rats. Experimental groups were compared with the diabetic control rats. Activity is expressed as: 50% of inhibition of epinephrine auto oxidation per min for SOD; µ moles of hydrogen peroxide decomposed per min. for catalase; μmoles of glutathione oxidized per min. for GPx. **significantly different from control group at p<0.01