Groups
Treatment/Dose (mg/mL)
Liver Kidney Heart
GSH
mg/100g. tissue
GPx
U/mg. protein
SOD
U/mg. protein
CAT
U/mg. protein
GSH
mg/100g. tissue
Gpx
U/mg. protein
SOD
U/mg. protein
CAT
U/mg. protein
GSH
mg/100g. tissue
GPx
U/mg. protein
SOD
mg/100g. tissue
CAT
mg/100g. tissue
Normal Control 142.34
± 5.261
17.14
± 2.05
13.89
± 3.71
65.19
± 4.71
101.00
± 8.38
8.06
± 1.43
10.44
± 2.71
43.28
± 3.48
115.48
± 9.04
13.59
± 2.50
9.08
± 1.91
27.46
± 2.83
Control + CAMBA (25mg/kg) 139.68
± 7.90
16.05
± 3.22
12.44
± 1.75
60.34
± 5.38
98.07
± 5.40
8.11
± 2.07
10.25
± 3.13
46.08
± 5.23
114.50
± 6.37
13.33
± 2.01
10.26
± 1.79
29.04
± 5.26
Control + CAMBA (50mg/kg) 140.57
± 8.11
18.10
± 4.06
13.06
± 2.30
64.35
± 7.11
104.71
± 10.59
8.98
± 1.90
11.17
± 2.39
46.69
± 7.08
117.92
± 10.25
14.05
± 2.67
12.74
± 3.08
28.11
± 3.29
Diabetic Control 87.45
± 5.08**
7.44
±1.15**
4.19
±1.33**
37.94
±4.38**
55.06
±4.38
4.56
±0.58**
5.94
±1.47**
27.93
±4.66**
76.82
±6.08**
5.99
±1.85**
6.55
± 1.13**
15.95
± 2.18**
Diabetic + CAMBA (25mg/kg) 122.73
± 8.46**
11.82
±2.00**
7.86
±2.35**
50.08
±6.26
75.97
±6.84
6.27
±1.08**
7.16
±0.57**
35.00
±4.86**
84.26
±4.75**
8.22
±2.04**
7.72
± 1.94**
22.49
± 3.30**
Diabetic +CAMBA (50mg/kg) 138.83
± 7.93**
15.77
±2.57**
11.46
±3.24**
59.63
±4.81
89.44
±7.65
9.63
±2.48**
10.39
±2.71**
41.60
±4.22**
104.13
±7.38**
11.29
±2.41**
10.55
± 2.03**
25.37
± 4.02**
Diabetic +Glibenclamide(5mg/kg) 128.44
± 6.50**
12.85
±1.48**
9.59
±2.18**
54.16
±3.99
80.39
±5.07
8.15
±1.83**
9.80
±2.11**
30.85
±2.79**
90.44
±8.06**
9.08
±2.11**
9.12
± 1.60**
19.70
± 3.46**
Values represent the mean ± SE (n=8). Diabetic control rats were compared with normal control rats. Experimental groups were compared with the diabetic control rats. Activity is expressed as: 50% of inhibition of epinephrine auto oxidation per min for SOD; µ moles of hydrogen peroxide decomposed per min. for catalase; μmoles of glutathione oxidized per min. for GPx. **significantly different from control group at p<0.01
Table 6: Effect of CAMBA on liver, kidney and heart GSH, GPx, SOD and CAT in control and experimental groups of rats.