|
Receptor |
Number of VS
hits |
Number of VS
verified hits* |
Hit Rate in % |
Number selective hits (Hit Rate^) |
|
H3 |
19 |
13 |
68% |
10
(76%) |
| H4 |
79 |
36 |
45% |
2 (5%) |
| |
74 |
33 (dual) |
44% (dual) |
17 (51%) |
*Hits were defined as compounds with ≥ 50% inhibition at 20μM
^Percentage of the hits that were also selective or dual active compounds |