Entries Mw/M+H (Da) tR (min)b Hemolytic toxicity
EC50 (μg/mL)c
calcd founda
Loloatin C 1336.66044 1336.66123 53.36 85
L1 841.35153 841.35416 13.47 120
L1.1 954.43559 954.43776 23.98 130
L1.2 955.43084 955.43181 10.23 >250
L2 855.36718 855.36797 17.08 >250
L2.1 968.45334 968.45626 27.72 237
L3 903.36718 903.36987 21.06 160
L3.1 1016.45124 1016.45068 34.25 135
L3.2 1017.44649 1017.45002 16.66 >250
a HRMS
b Retention time was measured using analytical column (see Experimental Section)
cEC50 was defined as the concentration of peptides producing 50% hemolysis
Table 2: Physicochemical Properties and Hemolytic Toxicities of the Peptides.