Compound
IC
50
HPV16 (μM)
IC
90
HPV16 (μM)
n (replicates)
NV1020
5
>>10
4
NV1023
5
10
2
NV1028
0.10
1.3
4
NV1030
0.13
1.3
4
Table 1:
IC
50
and IC
90
values against HPV16 are shown for nearly isomeric polyamides NV1020, NV1023, NV1028 and NV1030, all with the same putative DNA recognition motif.