compounds
Immobility time(seconds)
Control
183 ± 5.3
DMSO
160 ± 10.2
IV
a
78 ± 2.9 *
VI
b
71.4 ± 5.4 *
IV
c
80 ± 5.7 *
VI
c
57.8 ± 4.9 *
IV
d
51.8 ± 3.2 *
clozapine
121 ± 6.6 *
Table 2:
Evaluation of C.N.S. depressant activity of compounds and clozapine (3 mg/kg, i.p.) on mice using the forced swim test.