S.No Entry R1 R2 R3 R4 R5 4Yield(%)a
1 4a (JBIR) H OMe OH H H 88
2 4b H OMe H H H 90
3 4c OMe H H H H 90
4 4d H H OMe H H 90
5 4e H OMe OMe H H 89
6 4f OMe OMe OMe H H 88
7 4g H OMe OMe OMe H 87
8 4h H OCH2O H H 86
9 4i Cl H H H H 85
aIsolated yields
Table 1: Synthesis of N1, N6-dihydrocinnamyl putrescine bisamides.