Compound Gscore Interaction H-bond distance
TD1 -8.023 Cys285 2.480
TD2 -7.404 Ser342
Ser342
2.527
3.183
TD3 -8.895 Ser342 3.451
TD4 -8.422 Arg288 2.609
TD5 -8.108 Ser342 2.597
TD6 -8.115 - -
TD7 -8.392 Ser342 3.206
Rosiglitazone (Standard) -9.94 Glu343 2.827
Table 5: Gscore and Hydrogen bonding distances for the designed molecules.