Table 3

Quercetin
	n	0.1	0.3	1	3	10	30	100 μM
Ⅰ Constriction induced by Norepinephrine
A)
Control (Endothelium+)	10	1.7±0.5	3.6±0.9¹⁾	6.9±0.9²⁾	12.4±1.1²⁾	32.0±5.7³⁾	54.1±8.4³⁾	97.8±3.7³⁾
Ca2+-free	5	2.1±1.5	3.1±1.4	9.0±2.0	12.8±3.3	22.6±2.5	45.0±3.3^a)	67.5±7.7^a)
Nicardipine	5	0.0±0.0	1.4±1.4	1.4±1.4	1.4 ±1.4^a)	6.8±3.6^a)	15.0±7.2^a)	61.2±16.6^a)
Ro-31-8425 (0.1μM)	5	1.5±1.0	3.0±1.9	6.6±2.5	12.8±4.0	23.0±4.9	42.8±4.2^a)	80.8±2.6^b)
Gӧ6983 (0.1μM)	5	1.0±0.6	2.0±1.2	2.8±1.7	8.1±2.5	18.8±3.5	40.0±6.2^a)	84.6±7.7^a)
B)
Endothelium-denuded	5	1.5±1.3	3.1±1.6	6.9±1.8	11.2±2.4¹⁾	30.8±4.9²⁾	44.1±4.2²⁾	77.9±2.3³⁾
+TEA (100μM)	5	1.0±0.75	3.0±1.3	5.5±2.6	9.2±3.6	17.9±4.2^a)	31.7±4.9^a)	62.5±4.9^a)
C)
L-NMMA(100μM )+Indomethacin (10μM)	5	1.9±0.8	4.1±1.3	6.8±1.3¹⁾	11.0±2.0²⁾	18.2±4.7²⁾	30.4±6.2³⁾	65.2±6.6³⁾
+high K+(30mM)	5	0.5±0.3	2.6±1.5	5.1±1.6	9.4±2.3	13.6±1.9	24.4±3.9^a)	41.0±5.7^a)
+TEA (100μM)	5	1.2±0.5	1.8±1.5	1.8±1.5	4.0±4.0	8.5±5.5	16.8±7.0^a)	43.8±9.5^a)
+Charybdotoxin	5	2.1±1.3	3.8±2.6	4.2±2.0	4.5±2.3	16.8±3.6	28.2 ±2.7	63.4±11.8
+Apamin	5	0.6±0.6	0.8±0.8	1.6±1.6	3.7±2.7	5.1±1.6	9.4±2.4^b)	47.1±11.1^b)
Ⅱ Constriction induced by KCL
A)
Control	10	0.0±0.0	0.8±0.4	0.9±0.4	0.9±0.4	8.8±2.2¹⁾	29.9±6.0²⁾	92.8±4.0³⁾
Ro-31-8425 (0.1μM)	5	0.0±0.0	0.0±0.0	0.3±03	1.0±0.6	9.6±3.1	16.0±3.1^a)	75.6±7.9^a)
Gӧ6983 (0.1μM)	5	0.0±0.0	1.0±1.0	1.1±1.0	1.4±1.2	8.0±1.2	26.8±2.8	49.5±13.7^a)

Values (%) represent mean ± S.E.M. ¹⁾ and ^a) : p<0.05, ²⁾ and ^b):p<0.01, ³⁾: p<0.001.I:A)The symbol of ^a), ^b) indicate significant difference as compared with control (endothelium (+)) values. B)The symbol of ^a) indicate indicates significant difference as compared with endothelium-denuded.C) The symbol of ^a), ^b) indicates significant difference as compared with L-NAME+indomethacin. Ⅱ: A) Symbols of ¹⁾, ²⁾, and ³⁾mean significant differences in comparison between effects of quercetin itself at each concentration and the maximal constriction induced by KCl. The symbol of ^a) indicates significant difference as compared with control (quercetin alone) values.

Table 3: The alteration of endothelium-independent vasodilatation induced by quercetin in rat aorta.