| Mean wound diameter (mm) ± SEM |
| Day |
Untreated |
Cream only |
S/S (1% w/w) |
MMAL
(10% w/w) |
AqACL
(5% w/w) |
EACL
(5% w/w) |
| 1 |
27.00 ± 1.09 |
30.20 ± 2.22 |
25.80 ± 0.96 |
22.80 ± 0.58 * |
22.60 ± 0.67 * |
25.40 ± 0.40 |
| 3 |
20.54 ± 0.45 |
24.60 ± 1.32 |
19.60 ± 0.87 |
21.40 ± 0.60 |
19.40 ± 1.12 |
22.80 ± 1.06 |
| 5 |
19.94 ± 0.36 |
23.60 ± 1.83 |
17.32 ± 0.84 |
21.20 ± 1.24 |
17.80 ± 0.86 |
20.20 ± 0.80 |
| 7 |
18.28 ± 0.75 |
19.00 ± 1.22 |
14.00 ± 0.79 * |
17.20 ± 0.96 |
14.40 ± 0.67 |
17.20 ± 0.80 |
| 9 |
15.26 ± 0.82 |
11.80 ± 0.37 |
9.88 ± 0.91** |
9.20 ± 0.58 *** |
9.60 ± 0.60 ** |
11.60 ± 0.92 |
| 11 |
10.84 ± 0.41 |
8.20 ± 0.20 |
7.08 ± 0.90 |
6.80 ± 0.80 * |
6.60 ± 0.97 * |
8.40 ± 0.74 |
MMAL=methanol leaf extract of M. arboreus; AqACL=aqueous leaf of A. cordifolia; EACL=ethanol leaf extract of A. cordifolia; S/S= silver sulphadiazine; N=5 rats per group;
*p<0.05, **p<0.01, ***p<0.001 were considered statistically significant compared with the untreated wounds. |