Figure 3(a): Redocked conformer of ligand AFN941 in active site of the protein EGFR (PDB ID 2ITW). 3(b). 2D representation of ligand AFN941. 4(a). Active site of the protein EGFR (PDB ID 2ITW) of molecular model compound 68. 4(b). Schematic 2D representation of interactions of protein EGFR with compound 68in binding pocket. Active site amino acid residues are represented as tubes, while the inhibitor is shown as ball and stick model with the atoms colored as carbon: green, nitrogen: blue, oxygen: red. Hydrogen bond interactions are represented by yellow dotted lines. Pose view: black dashed lines - hydrogen bonds, salt bridges, metal interactions; green solid lines - hydrophobic interactions; green dashed lines - Pi-Pi, Pi-cation interaction.