Figure 7(a): Redocked conformer of ligand AMP-PNP in active site of protein EGFR (PDB ID 2ITX). 7(b) 2D representation of ligand AMP-PNP. 8(a). Active site of the protein EGFR (PDB ID 2ITX) with Molecular model compound 80.8(b).Schematic 2D representation of interaction of compound 80 with protein EGFR in the binding pocket. Active site amino acid residues are represented as tubes, while the inhibitor is shown as ball and stick model with the atoms colored as carbon: green, hydrogen: cyan, nitrogen: blue, oxygen: red. Hydrogen bond interactions are represented by yellow dotted lines Pose view: black dashed lines - hydrogen bonds, salt bridges, metal interactions; green solid lines - hydrophobic interactions; green dashed lines - Pi-Pi, Pi-cation interaction.