|
| Figure 2: Synthetic scheme to prepare the hybrid compounds. |
| a.Sodiumethoxide/DMF/95-100 0C or Sodium carbonate/95% ethanol/85 0C for intermediates 1 and 6, respectively. |
| b. SnCl2 /CH3COOH/ HCl//9500C |
| c. Chloracetylchloride/CH3COOH |
| d. Homoveratrylamine for 4&9, or N-methylhomoveratrylamine for 5 &10/ benzene/reflux |